Until recently, there was thought to be no effective clinical treatment for unexplained recurrent miscarriage. However, CCRM researchers have found that a technique that examines all 23 pairs of chromosomes in a human blastocyst (day five embryo), known as comprehensive chromosome screening (CCS), is an effective clinical treatment for unexplained recurrent miscarriages.
It is well known that aneupliod embryos (chromosomally abnormal) will typically result in spontaneous miscarriage. CCRM clinicians recently conducted a study employing CCS and cryopreservation techniques, which allows them to select and transfer only blastocysts that have 23 pairs of chromosomes in a frozen embryo transfer. Out of 33 patients who had at least one chromosomally normal embryo transferred, 87.9% had clinical pregnancy; only one pregnancy resulted in a miscarriage.
This exciting discovery will open doors for many couples wanting to have children who previously had no where to turn.
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