Comprehensive Chromosome Screening (CCS)
CCS testing is performed on a few cells biopsied from a day 5 embryo called a blastocyst. The genetic material of the embryo is not altered in any way during CCS. During the time it takes to perform CCS, blastocysts are cryopreserved using a quick freezing method called vitrification. Embryo survival after vitrification is extremely high at 98%.
Waiting for the CCS results and vitrifying the embryos has an added benefit to the patient. It offers some time for the patient’s body to return to a normal hormonal state after ovarian stimulation. Studies have shown that transferring embryos into a uterus that is in a more natural hormonal state enhances the likelihood of implantation and a healthier outcome.
After CCS testing, only embryos that have the correct number of chromosomes are selected for transfer. CCS is provided to patients through an Institutional Review Board (IRB) – approved ongoing clinical study.
Who should consider CCS?
CCS is not recommended for all infertility patients. Those who may consider CCS include the following:
- Women 35 years of age or older
- Women with a history of repeated miscarriage
- Women with a previous pregnancy involving a chromosomal abnormality
- Women who have had multiple failed IVF cycles
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