Intrauterine Insemination (IUI) in Greenville, SC

IUI clinic serving the greater Greenville metropolitan area

Intrauterine insemination (IUI), commonly referred to as artificial insemination, is a fertility treatment option that involves placing washed sperm directly into the uterus to increase the chances of fertilization. At CCRM Fertility of Greenville, we offer state-of-the-art IUI treatments & compassionate expertise that are both customized to meet the individual needs of our patients.

Our IUI process at CCRM Fertility of Greenville

While IUI continues to be the gold standard of infertility treatment in the medical community, at CCRM Fertility of Greenville, we understand that every patient is unique. That’s why we begin the IUI process with a comprehensive evaluation of both partners, including a thorough medical history, physical examination, and laboratory testing. Our experienced team of reproductive specialists will then collaborate with you to develop a personalized treatment plan that addresses your specific needs and goals.

Before beginning IUI treatment, patients may undergo ovulation induction to stimulate the ovaries and increase the chances of successful fertilization. This may include taking oral medications or receiving injectable hormones, depending on your individual needs.

Once the ovaries are stimulated, we will monitor your cycle closely using ultrasound imaging and hormone testing. When the follicles have reached the appropriate size, we will administer a trigger shot of human chorionic gonadotropin (hCG) to trigger ovulation.

Approximately 24-36 hours after receiving the hCG shot, you will return to our clinic for the IUI procedure. During the procedure, we will insert a thin catheter through the cervix and into the uterus, where washed sperm will be injected directly into the uterus. The procedure typically takes less than 30 minutes, and patients can return to normal activities immediately afterward.

Who are ideal candidates for intrauterine insemination?

Ideal candidates for intrauterine insemination include:

  • Couples who have been trying to conceive for at least six months without success
  • Couples using donor sperm or same-sex couples who wish to conceive
  • Couples experiencing male infertility, such as low sperm count or decreased sperm motility
  • Women who have ovulation problems, hormonal imbalances, or other fertility issues, for whom IUI may be recommended as a first-line treatment option.

What are the requirements for IUI in Greenville?

To receive IUI treatment at CCRM Fertility of Greenville, patients must meet the following criteria:

  • Undergo a comprehensive evaluation to determine the underlying cause of infertility, which may include blood tests, semen analysis, and other diagnostic tests
  • Ovulate regularly, or be able to undergo ovulation induction
  • Have open and unblocked fallopian tubes
  • The male partner must have a sufficient sperm count and motility

IVF vs. IUI: which is right for you?

Deciding between IUI and IVF is a personal choice—and the right option depends on your medical history, age, goals, and how quickly you want to move forward.

IUI (Intrauterine Insemination) is often considered a first step in fertility treatment. It’s less invasive and more affordable, making it a common choice for:

  • Mild male factor infertility
  • Unexplained infertility
  • Single parents by choice
  • LGBTQIA+ individuals and couples
  • Younger patients with no major reproductive concerns

     

IVF (In Vitro Fertilization) involves more advanced technology and a higher level of control. It is often recommended if:

  • You’ve tried IUI without success
  • There are known conditions like endometriosis, low ovarian reserve, or blocked fallopian tubes
  • You’re considering genetic testing or sex selection
  • You want to freeze embryos for future use
 

While IUI may be a good starting point, IVF generally offers higher success rates per cycle. Our team at CCRM Fertility of Greenville will help you compare your options based on clinical data, personal priorities, and financial considerations so you can move forward with clarity and confidence.

Finding the right fertility specialist is not always an easy task when you are looking for a fertility clinic in Greenville that can accommodate your needs. The double board-certified reproductive endocrinologists at CCRM Fertility of Greenville can help you realize your dream of parenthood and will support you every step of the way.

A woman with long, wavy light brown hair wearing a green top and two delicate necklaces smiles at the camera against a light blue background.
Rachel Beverley
MD
A man in a navy suit with a light blue shirt and a red striped bow tie smiles at the camera against a light blue background.
Creighton E. Likes, III
MD, MS

The cost of intrauterine insemination in Greenville, SC

The cost of IUI treatment at CCRM Fertility of Greenville ranges from $950-$4,350, but varies depending on a number of factors, including the individual patient’s needs and the specific treatment plan that is recommended. However, we strive to provide affordable and accessible fertility treatment options to all of our patients.

CCRM Fertility of Greenville participates with numerous insurance and fertility benefit providers. Our team is committed to helping our patients understand their insurance coverage and identify any potential gaps in coverage that may exist. We also partner with Future Family to offer financing options and offer multi-cycle packages to help make treatment more affordable.

Insurance coverage for IUI in Greenville

If you’re considering IUI as part of your fertility care, it’s important to understand how insurance coverage works in South Carolina. Unlike some states, South Carolina does not require insurance plans to cover infertility diagnosis or treatment, including intrauterine insemination (IUI). For patients in the Greenville area, coverage depends entirely on the terms of an individual or employer-sponsored health plan.

Potentially Covered Services (Plan-Dependent)
When fertility benefits are offered, coverage may include some or all of the following services when deemed medically necessary:

  • Initial fertility consultations and diagnostic testing
  • Cycle monitoring appointments and ultrasounds
  • IUI procedures
  • Fertility medications associated with the treatment cycle
 

Not all plans include IUI benefits, and limits may apply based on diagnosis, number of treatment cycles, or how infertility is defined. These definitions can affect single patients and LGBTQIA+ individuals, even when other medical services are covered.

Services Often Not Covered
Patients pursuing IUI with donor sperm should be aware that donor-related expenses are typically not included in insurance coverage. This often includes:

  • Donor sperm acquisition
  • Sperm storage and shipping fees
 

At CCRM Fertility serving the Greenville area, our financial counselors will help you navigate your insurance benefits with clarity. We’ll verify what your plan covers, explain expected out-of-pocket costs, and discuss self-pay and financing options so you can move forward with confidence throughout your IUI journey.

Accepted fertility insurances in Greenville, SC

We participate in several insurance plans and offer financing options for those not covered by insurance. 

  • Aetna**
  • Assure
  • Carrot*
  • Cigna (excludes Local Plus, Sure Fit, and South Carolina Connect)
  • Cofinity PPO
  • Evicore
  • Great West
  • Kaiser
  • Livestrong
  • Maven*
  • MOREhealth
  • Optum Fertility Solutions
  • Progyny*
  • United Healthcare (includes affiliates, such as UMR, Oxford Health, Optum, Harvard Pilgrim, Golden Rule, etc. We do not participate with most EPO plans)**
 

*Carrot, Maven and Progyny fertility benefits vary based on your employer. All Progyny patients (new or existing at a clinic) must first call their Progyny Patient Care Advocate (PCA) for authorization before scheduling an appointment at CCRM.

**CCRM Fertility of South Carolina is proud to be designated as both an Aetna and a United Healthcare Center of Excellence.

We aim to ensure that every patient has access to high-quality fertility treatment, regardless of their financial situation.

What about LGBTQIA+ and single patients seeking IUI?

Insurance coverage can be especially complex for LGBTQIA+ individuals seeking IUI or single parents by choice seeking IUI. Some plans may not recognize the need for fertility treatment unless there’s a defined infertility diagnosis based on heteronormative criteria (e.g., 12 months of unprotected intercourse without pregnancy).

Our team can help you navigate this with care, advocating for your access to fertility benefits and outlining financial options when coverage is limited.

Schedule your IUI treatment with CCRM Fertility of Greenville today

At CCRM Fertility of Greenville, we provide advanced testing and expert guidance to help you take the next step toward parenthood. Schedule your appointment today to get the answers you need.

CCRM Fertility of Greenville

700 Executive Center Dr, Suite 300
Greenville, SC 29615

Phone: (864) 412-1950
Fax: (864) 412-0640

Hours

Regular Hours: Monday-Friday: 7:30am – 4:00pm

Monitoring hours: Morning and weekend monitoring by appointment only